| Paullones represent a novel class of small molecule cyclin-dependent kinase (CDK) inhibitors. Alsterpaullone is a potent inhibitor of CDK1/cyclin B (IC50=0.035μM). High in vitro anti-tumor potency. | |
| Reference Price: | $58.00 Click to Order |
| More Information: | 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one - C16H11N3O3 - Cancer Research - Inhibitor - Leost, M. et al. - Paullones are Potent Inhibitors of Glycogen Synthase Kinase-3ß and Cyclin-Dependent Kinase 5/p25. - Eur. J. Biochem. - Sausville, E.A. et al. - Inhibition of CDKs as a Therapeutic Modality - Ann. NY Acad. Sci. - Schultz, C. et al. - Paullones, a Series of Cyclin-Dependent Kinase Inhibitors: Synthesis, Evaluation of CDK1/cyclin B Inhibition, and In Vitro Antitumor Activity. - J. Med. Chem. |
| Paullones represent a novel class of small molecule cyclin-dependent kinase (CDK) inhibitors. Alsterpaullone is a potent inhibitor of CDK1/cyclin B (IC50=0.035μM). High in vitro anti-tumor potency. | |
| Reference Price: | $58.00 Click to Order |
| More Information: | 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one - C16H11N3O3 - Cancer Research - Protein Kinases - Leost, M. et al. - Paullones are Potent Inhibitors of Glycogen Synthase Kinase-3ß and Cyclin-Dependent Kinase 5/p25. - Eur. J. Biochem. - Sausville, E.A. et al. - Inhibition of CDKs as a Therapeutic Modality - Ann. NY Acad. Sci. - Schultz, C. et al. - Paullones, a Series of Cyclin-Dependent Kinase Inhibitors: Synthesis, Evaluation of CDK1/cyclin B Inhibition, and In Vitro Antitumor Activity. - J. Med. Chem. |
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